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Manufacture and sale of sildenafil citrate drugs is common in China, where Pfizer's patent claim is not widely enforced. Sildenafil protects cyclic guanosine monophosphate (cGMP) from degradation by cGMP-specific phosphodiesterase type 5 (PDE5) in the corpus cavernosum. The pharmacokinetics of sildenafil in patients with severely impaired hepatic function have not been studied. Maximum observed plasma concentrations are reached within 30 to 120 minutes (median 60 minutes) of oral dosing in the fasted state.

Less common side effects may include nausea, dizziness, rash, increased urination, and diarrhea. In rare cases, Generic Viagra may cause an erection that lasts longer than 4 hours. Other rare side effects may include an irregular heartbeat, chest pain, and sudden vision loss. Viagra contains the active ingredient sildenafil which is available as a generic medication. Often called the little blue pill, it works by improving blood flow to your penis, making it easier to get an erection hard enough for sex. It’s one of the most effective ED treatments available, working for up to 74% of men who take it.

It is important to take this medication exactly as prescribed by your doctor. Do not take higher doses of this medication than those prescribed by your doctor. Contact your doctor if you take a greater dose of sildenafil than prescribed. Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

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